| Klotho: a natural hormone that slows aging and cancerhe soluble protein Klotho was initially widely believed to be an anti-aging factor: knockout mice showed signs of accelerated aging and tumor formation. More recent results have called that into question, suggesting that Klotho mutants mimic progeria without actually undergoing bona fide accelerated aging. The newest study of the protein demonstrates at the molecular level that Klotho inactivates a pro-aging pathway, and also slows the growth of breast cancer. While still controversial, the idea that Klotho is an anti-aging factor is still very much alive. |
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